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409835Bio Roundup: Cerevel’s Shell, Thrive’s Rise, Drug Price Drama & More
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409770AlloVir’s IPO Raises $276M to Test Cell Therapies in Transplant Patients
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    Kymera Therapeutics has a pipeline of preclinical drug candidates that use an experimental approach to get rid of disease-causing proteins and it’s now looking to tap the public markets to finance tests of the technology in humans.

    In paperwork submitted to... Read more »

    免费外网加速器7/31/20
  • Bio Roundup: Cerevel’s Shell, Thrive’s Rise, Drug Price Drama & More

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    The biotech IPO market is buzzing but Cerevel Therapeutics is showing that there’s more than one path to the public markets. This week the neuroscience drug developer reached a deal to 免费翻国外墙的app with publicly traded Arya Sciences Acquisition Corp II.

    If... Read more »

    Frank Vinluan7/31/20
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    Another biopharma has signed up to use Sangamo Therapeutics’ gene editing technology to develop therapies that can address disease by heightening or depressing a gene’s activity level.

    Sangamo on Thursday announced that Novartis (NYSE: NVS) had agreed to shell out... 能上国外网的免费加速器

    Sarah de Crescenzo7/30/20
  • AlloVir’s IPO Raises $276M to Test Cell Therapies in Transplant Patients

    AlloVir’s IPO Raises $276M to Test Cell Therapies in Transplant Patients

    AlloVir is the latest biotech company to go public, raising about $276.3 million to pull its cell therapies off the shelf and run multiple clinical trials testing them in stem cell and organ transplant patients.

    On Thursday, Cambridge, MA-based AlloVir (NASDAQ:... Read more »

    Frank Vinluan7/30/20
  • Amid Boom Days for Biotech, Inhibrx Lines Up Another IPO Effort

    Amid Boom Days for Biotech, Inhibrx Lines Up Another IPO Effort

    Public investors are betting big on biotechs, and Inhibrx is looking to capitalize on the industry’s recent resurgence of initial public offerings.

    The La Jolla, CA-based company, which is developing drugs for cancer and a rare respiratory disease, has again applied... Read more »

    Sarah de Crescenzo7/29/20
  • Roche Pays $120M for Rights to UCB’s Tau-Targeting Alzheimer’s Drug

    Roche Pays $120M for Rights to UCB’s Tau-Targeting Alzheimer’s Drug

    As the Alzheimer’s disease world continues to closely follow the development of therapies that break up clumps of beta amyloid on patients’ brains, Roche is placing a bet on another approach via a deal that secures rights to a clinical-stage UCB... Read more »

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  • 2020 National Xconomy Awards Finalists Announced

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    After receiving and reviewing nearly 600 entries spanning 10 award categories, Xconomy is thrilled to announce the 2020 Xconomy National Awards Finalists.

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    海外永久免费加速器7/29/20
  • Omega Therapeutics Lands $85M to Tap Into “Control Room” of Biology

    Omega Therapeutics Lands $85M to Tap Into “Control Room” of Biology

    The promise of gene therapies and gene-editing drugs is a long-lasting treatment that’s potentially a cure. But making permanent genetic changes means any accompanying problems could be long-lasting as well, says Omega Therapeutics CEO Mahesh Karande.

    Omega is developing technology that... Read more »

    Frank Vinluan7/29/20
  • Nura Bio Debuts With $73M and Plan to Develop “Neuroprotective” Drugs

    Nura Bio Debuts With $73M and Plan to Develop “Neuroprotective” Drugs

    Damage to axons, the slender tendrils through which nerve cells communicate, is an early indication of several neurological diseases. Nura Bio, which formed around new research into a mechanism underlying axonal degeneration, made its public debut Wednesday with a $73 million... Read more »

    Sarah de Crescenzo7/29/20
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    Thrive Adds $257M, Plans Pivotal Trial of Early Cancer Detection Test

    Thrive Earlier Detection, one of the companies vying to be the first to commercialize a blood test that can uncover cases of cancer before symptoms arise, has raised $257 million and announced plans to evaluate its CancerSEEK test in a registrational... 免费跨国加速器

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  • Pfizer, BioNTech Choose Full Spike Protein for Pivotal Vaccine Test

    Pfizer, BioNTech Choose Full Spike Protein for Pivotal Vaccine Test

    Pfizer and BioNTech’s COVID-19 vaccine research started with multiple approaches—four shots on the messenger RNA goal. The partners have narrowed their choices to one for pivotal testing, and that candidate takes the same tack as other companies trying to address... Read more »

    Frank Vinluan7/28/20
  • Telehealth Firm AristaMD Adds $24M to Link Primary Docs With Specialists

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    Telemedicine isn’t just another way to connect patients with doctors. AristaMD has carved out a niche in connecting doctors with, well, other doctors.

    The San Diego-based telehealth company’s software links primary care physicians and medical specialists through virtual consultations, communication that... Read more »

    Sarah de Crescenzo7/27/20
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    AstraZeneca to Pay $1B to Team Up With Daiichi Sankyo Again in Cancer

    AstraZeneca’s partnership with Daiichi Sankyo led to FDA approval of an antibody cancer drug late last year. Now the British pharmaceutical giant is paying $1 billion up front to join forces on another antibody drug addressing a different cancer target.

    The... Read more »

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    The lack of diversity in clinical trials is a serious problem that’s persisted for decades. Black Americans—who make up 20 percent of US multiple myeloma patients and are twice as likely to be diagnosed—have only accounted for 4.5 percent of... Read more »

    Liz Beatty7/27/20
  • Gilead Gets Another CAR-T Approval, This Time for Mantle Cell Lymphoma

    Gilead Gets Another CAR-T Approval, This Time for Mantle Cell Lymphoma

    The FDA on Friday approved a Gilead Sciences drug developed for treating mantle cell lymphoma, paving the way for the company to commercialize its second cancer cell therapy.

    Approval for the drug, brexucabtagene autoleucel (Tecartus), covers patients whose cancer has relapsed... Read more »

    Frank Vinluan7/24/20
  • Bio Roundup: Jazz Drug OK’d, Gilead’s Bet, Moderna Patent Decision & More

    Bio Roundup: Jazz Drug OK’d, Gilead’s Bet, Moderna Patent Decision & More

    EQRx launched in January during the JP Morgan Healthcare Conference with an audacious pledge to create 10 new drugs in as many years and then sell them at “dramatically” lower prices than existing medicines. But it offered few specifics about how... 国外免费加速器下载

    Sarah de Crescenzo7/24/20
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    FDA Lifts CymaBay Drug Hold, Tests to Resume in Rare Liver Disease PBC

    The FDA has 免费翻国外墙的app a hold on clinical trials for an experimental CymaBay Therapeutics drug in three liver diseases, clearing the way for tests to resume in all of them. But the company won’t be pressing forward in the biggest one,... Read more »

    Frank Vinluan7/23/20
  • Jazz Pharma Gets FDA Nod for New Drug to Treat Narcolepsy Symptoms

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    [Corrected 7/23/20, 10:13 am. See below.] Jazz Pharmaceuticals has received FDA approval for a narcolepsy drug that it has developed as a lower-sodium successor to its biggest moneymaker, a treatment that was first approved in 2002 to reduce attacks of... Read more »

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  • Vesigen Nabs $28M to Wrap “ARMMS” Around Large Molecule Drug Delivery

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    It’s not enough for a cell or gene therapy to reach a cell, it must also get inside it to access most of the validated drug targets. Vesigen Therapeutics is developing technology that could best other approaches at penetrating the cellular... Read more »

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    Seer Raises $55M to Commercialize Tools to Analyze the Proteome

    Illumina led the genomics revolution, developing tools that have changed how scientists discover drugs and how clinicians treat patients. Startup Seer is making the case that its technology for analyzing the proteome—the complement of proteins that cells, tissues, and organs produce—will... Read more »

    Sarah de Crescenzo7/22/20
  • Olema Adds $54M to Start Human Tests of Breast Cancer Drug Candidate

    Olema Adds $54M to Start Human Tests of Breast Cancer Drug Candidate

    Olema Oncology has raised $54 million to advance its lead drug candidate into human tests, having been working in stealth since 2007 to develop a daily pill to treat women with breast cancer whose disease is driven by the hormone estrogen.

    San Francisco-based... Read more »

    Sarah de Crescenzo7/22/20
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    Freeline Therapeutics and Checkmate Pharma Make Opening IPO Moves

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    Freeline is raising cash to ensure that its lead program, a prospective hemophilia B gene... Read more »

    Frank Vinluan7/21/20
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    Elevation Oncology Debuts With $32.5M to Develop Targeted Cancer Drugs

    Elevation Oncology formed last year with $32.5 million in a Series A financing round led by the initial investor in Loxo Oncology, a company that blazed a trail developing cancer therapies based on genetic signature rather than tumor origin.

    On Tuesday... Read more »

    Sarah de Crescenzo7/21/20
  • Roche, Jnana Enter Drug R&D Alliance Targeting Metabolism’s Gatekeepers

    Roche, Jnana Enter Drug R&D Alliance Targeting Metabolism’s Gatekeepers

    Scientists know that proteins called solute carrier (SLC) transporters move substances important to metabolism across cellular membranes. But can drugs effectively hit these proteins to treat disease? Roche is paying startup Jnana Therapeutics $40 million to find out.

    The alliance announced... Read more »

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  • Gilead Sciences Splashes Out $300M for Tizona Stake & Option to Acquire

    Gilead Sciences Splashes Out $300M for Tizona Stake & Option to Acquire

    Gilead Sciences has made its second deal in as many months that puts the company first in line to acquire a biotech developing cancer immunotherapies.

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    浏览外网的免费加速器7/21/20
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    Acadia Halts Work on Depression Drug After Late-Stage Trial Failure

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  • Forge Bio’s Combo Model for Gene Therapies Attracts $40M in Funding

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    Forge Biologics has something rare for most early-stage biotech startups: revenue from customers. Now it has $40 million to expand its model, which places contract manufacturing alongside the development of its own gene therapies, the most advanced of which is being... Read more »

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    GlaxoSmithKline is expanding its capabilities in messenger RNA (mRNA) research through a new alliance with CureVac spanning up to five programs targeting infectious disease pathogens.

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  • Exalys Launches With $15M to Treat Postoperative Delirium & More

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  • MeiraGTx, J&J See Phase 3 Test Ahead for Vision Loss Gene Therapy

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    Sarah de Crescenzo7/17/20
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Xconomist ForumExpert Insight and Opinion

  • Clinical Trial Diversity Isn’t Just a Moral Issue–It’s a Scientific Imperative

    Liz Beatty
  • Creating Consistent Value in Biotech Without Diluting Stakeholders

    Alexis Peyroles
  • Lax Approval Requirements Yield Blockbusters That Don’t Work

    Andy Smith
  • Digital Health Survivors & Innovative Incumbents Must Team Up for True Disruption

    Bryony Winn
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    Bio Roundup: Blackstone’s Billions, Biogen Finishes Filing, Novavax at “Warp Speed” & More

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    Telehealth Firm AristaMD Adds $24M to Link Primary Docs With Specialists

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